A Complete Set of Equations for a Computational Model of Electrolyte and Water Transport along the Nephrons in a Mammalian Kidney

Abstract

To investigate kidney under different physiological and pharmacological conditions, we have developed and applied computational models of electrolyte and water transport along nephrons in a kidney. The models predict spredict luminal fluid flow, hydrostatic pressure, membrane potential, luminal and cytosolic solute concentrations, and transcellular and paracellular fluxes through transporters and channels. The complete set of model equations are presented here.