ShinyGPAS: Interactive genomic prediction accuracy simulator based on deterministic formulas
Abstract
BackgroundDeterministic formulas highlight the relationships among prediction accuracy and potential factors influencing prediction accuracy prior to performing computationally intensive cross-validation. Visualizing such deterministic formulas in an interactive manner may lead to a better understanding of how genetic factors control prediction accuracy.\n\nResultsThe software to simulate deterministic formulas for genomic prediction accuracy was implemented in R and encapsulated as a web-based Shiny application. ShinyGPAS (Shiny Genomic Prediction Accuracy Simulator) simulates various deterministic formulas and delivers dynamic scatter plots of prediction accuracy vs. genetic factors impacting prediction accuracy, while requiring only mouse navigation in a web browser. ShinyGPAS is available at: https://chikudaisei.shinyapps.io/shinygpas/.\n\nConclusionShinyGPAS is a shiny-based interactive genomic prediction accuracy simulator using deterministic formulas. It can be used for interactively exploring potential factors influencing prediction accuracy in genome-enabled prediction, simulating achievable prediction accuracy prior to genotyping individuals, or supporting in-class teaching. ShinyGPAS is open source software and it is hosted online as a freely available web-based resource with an intuitive graphical user interface.
02 /Specification & Classification
Click any tag to browse matching papers- Citations
- 15
- FWCI
- 0.72
- Field percentile
- top 29%
- Research Focus
- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- SeqBreed: a python tool to evaluate genomic prediction in complex scenarios
Miguel Pérez-enciso A, Lino C. Ramírez-Ayala, Laura M. Zingaretti·Genetics Selection EvolutionPeer-reviewed·Feb 10, 2020
- Estimation Of Genomic Prediction Accuracy From Reference Populations With Varying Degrees Of Relationship
Sang Lee, Sam Clark, Julius H. J. van der Werf·PLoS ONEPeer-reviewed·Dec 21, 2017
- GAS Power Calculator: web-based power calculator for genetic association studies
Jennifer Li Johnson, Gonçalo R. Abecasis·bioRxiv·Jul 17, 2017
- genomicSimulation: fast R functions for stochastic simulation of breeding programs
Kira Villiers, Eric G. Dinglasan, … Kai P. Voss‐Fels·G3 Genes Genomes GeneticsPeer-reviewed·Sep 2, 2022
- Robust estimation of heritability and predictive accuracy in plant breeding: evaluation using simulation and empirical data
Vanda Lourenço, Joseph Ochieng Ogutu, Hans‐Peter Piepho·BMC GenomicsPeer-reviewed·Jan 14, 2020
- A better design for stratified medicine based on genomic prediction
Sang Hong Lee, W.M. Shalanee P. Weerasinghe, … Julius Van der Werf·Scientific ReportsPeer-reviewed·Feb 9, 2017