Scientific ReportsSynthetic BiologyPeer-reviewed journal article
Demonstration of End-to-End Automation of DNA Data Storage
Christopher N. TakahashiiD, Bichlien H. NguyeniD, Karin StraußiD, Luís CezeiD
Abstract
We developed a complete end-to-end DNA data storage device. The device enables the encoding of data, which is then written to a DNA oligonucleotide using a custom DNA synthesizer, pooled for liquid storage, and read using a nanopore sequencer and a novel, minimal preparation protocol. We demonstrate an automated 5-byte write, store, and read cycle with the ability to expand as new technology is available.
- assay: DNA methylation
- assay: whole-genome sequencing
- research focus: database / resource
- approach: experimental assay
- Citations
- 137
- FWCI
- 5.54
- Field percentile
- top 3%
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