Analytical BiochemistryBiophysicsPeer-reviewed journal article
Using absorbance detection for hs-SV-AUC characterization of adeno-association virus
Nicholas R. LarsoniD, George M. Bou-AssafiD, Thomas Maxon LaueiD, Steven A. BerkowitziD
Abstract
Data are presented demonstrating that absorbance detection can be used during high-speed sedimentation velocity analytical ultracentrifugation (hs-SV-AUC) experiments to accurately characterize adeno-associated virus (AAV) drug products. Advantages and limitations of being able to use this detector in this specific type of SV-AUC experiment are discussed.
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- 4
- FWCI
- 0.44
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- 50th percentile
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