Connectivity profile and function of uniquely human cortical areas
Katherine BryantiD, Julia A. CamilleriiD, Shaun WarringtoniD, Guilherme Blazquez FrechesiD, Stamatios N. SotiropoulosiD, Saâd JbabdiiD, Simon Bodo EickhoffiD, Rogier B. MarsiD
Abstract
Quantitative comparison of the white matter organization of the human neocortex with that of the chimpanzee and macaque shows a wide distribution of areas with a uniquely human connectivity profile, including the frontal-parietal fiber systems and the temporal visual pathway. Functional decoding of these areas shows their involvement in language, abstract reasoning, and social information processing. Overall, these results counter models that assign primacy to prefrontal cortex for human uniqueness.
02 /Specification & Classification
Click any tag to browse matching papers- Citations
- 24
- FWCI
- 13.20
- Field percentile
- top 1%
- Organism
- Assay
- Research Focus
- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- A Quantitative Assessment of Prefrontal Cortex in Humans Relative to Nonhuman Primates
Chad J. Donahue, Matthew F. Glasser, … David C. Van Essen·Proceedings of the National Academy of SciencesPeer-reviewed·May 8, 2018
- Common Fronto-temporal Effective Connectivity in Humans and Monkeys
Francesca Rocchi, Hiroyuki Oya, … Christopher I. Petkov·NeuronPeer-reviewed·Jan 21, 2021
- Frontal cortex encodes action goals and social context in freely moving and socially interacting macaques
Jacopo Baldi, Éloïse Disarbois, … Pier Francesco Ferrari·bioRxiv·Oct 21, 2025
- Tracing cortical circuits in humans and non-human primates from high resolution connectomic, transcriptomic, and temporal dimensions
Christine J. Charvet, Kwadwo Ofori, … Andre J. W. van der Kouwe·bioRxiv·Apr 30, 2021
- Cytoarchitectonic similarity is a wiring principle of the human connectome
Alexandros Goulas, René Werner, … Claus C Hilgetag·bioRxiv·Aug 6, 2016
- Monosynaptic connections link functionally similar regions in human cortex
Rui Xu, Alan Bush, … Robert Mark Richardson·bioRxiv·May 20, 2026