Inference of nodavirus zoonotic transmission networks from publicly available sequencing data

Abstract

The potential for nodavirus zoonosis has been known for many decades. However, diseases associated with nodavirus infection in mammals has only been documented recently. Natural infection with nodaviruses have been observed in human handlers of aquatic animal tissues (covert mortality nodavirus), and in pigs (porcine nodavirus). Here, we infer the potential networks of transmission of these nodaviruses and explore their genetic diversity by mining publicly available datasets.