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bioRxivBioinformaticsPreprint

Geospatially informed representation of spatial genomics data with SpatialFeatureExperiment

Lambda MosesiD, Alik HuseynoviD, Joseph Matthew RichiD, Lior S. PachteriD

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Abstract

SpatialFeatureExperiment is a Bioconductor package that leverages the versatility of Simple Features for spatial data analysis and SpatialExperiment for single-cell -omics to provide an expansive and convenient S4 class for working with spatial -omics data. SpatialFeatureExperiment can be used to store and analyze a variety of spatial -omics data types, including data from the Visium, Xenium, MERFISH, SeqFish, and Slide-seq platforms, bringing spatial operations to the SingleCellExperiment ecosystem.

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