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GeneticsbioRxiv
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Genetic \"General Intelligence,\" Objectively Determined and Measured

Javier de la FuenteiD, Gail DaviesiD, Andrew David GrotzingeriD, Elliot M. Tucker–DrobiD, Ian J. DearyiD

Abstract

It has been known for 115 years that, in humans, diverse cognitive traits are positively intercorrelated; this forms the basis for the general factor of intelligence (g). We directly test for a genetic basis for g using data from seven different cognitive tests (N = 11,263 to N = 331,679) and genome-wide autosomal single nucleotide polymorphisms. A genetic g factor accounts for 58.4% (SE = 4.8%) of the genetic variance in the cognitive traits, with trait-specific genetic factors accounting for the remaining 41.6%. We distill genetic loci broadly relevant for many cognitive traits (g) from loci associated with only individual cognitive traits. These results elucidate the etiological basis for a long-known yet poorly-understood phenomenon, revealing a fundamental dimension of genetic sharing across diverse cognitive traits.

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02 /Specification & Classification

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