Real-Time Computation of Brain E-Field for Enhanced Transcranial Magnetic Stimulation Neuronavigation and Optimization

Abstract

Transcranial Magnetic Stimulation (TMS) coil placement and pulse wave-form current are often chosen to achieve a specified E-field dose on targeted brain regions. TMS neuronavigation could be improved by including real-time accurate distributions of the E-field dose on the cortex. We introduce a method and develop software for computing brain E-field distributions in real-time enabling easy integration into neuronavigation and with the same accuracy as 1st-order finite element method (FEM) solvers. Initially, a spanning basis set ( View larger version (27K): org.highwire.dtl.DTLVardef@1520141org.highwire.dtl.DTLVardef@d05835org.highwire.dtl.DTLVardef@4f1aa9org.highwire.dtl.DTLVardef@15f7b90_HPS_FORMAT_FIGEXP M_FIG O_FLOATNOFigure 8:C_FLOATNO Mean computational time for pre-processing stage (mode and field generation stage) for mri2mesh models (A) and headreco models (B). At any rank (mode), the time is calculated across 8 head models from 8 subjects.) C_FIG