GenRank: an R/Bioconductor package for prioritization of candidate genes

Abstract

SummaryModern high-throughput studies often yield long lists of genes, of which a fraction are of high relevance to the phenotype of interest. To prioritize the candidate genes of complex genetic traits, our R/Bioconductor package GenRank provides methods that are based on convergent evidence obtained from multiple independent evidence layers. The package facilitates an extensible framework that allows a further addition of novel methods for candidate gene prioritization.\n\nAvailability and ImplementationThe methods are implemented in R and available as a package in Bioconductor repository (http://bioconductor.org/packages/GenRank/).\n\nContactchakra.kanduri@gmail.com