Quantitative relationships for radiation induced chromosome instability: data analysis
Y.A. Eidelman, S.V. Slanina, V.S. Pyatenko, I.K. Khvostunov, S.G. Andreev
Abstract
The experimental observations demonstrate that different cell lines reveal various shape of dynamic curves for radiation-induced chromosomal instability (RICI). We analyzed our own and published data on RICI for three cell lines, CHO-K1, V79 and TK6, on the basis of the mechanistic RICI model. We demonstrate that all three dynamic curves can be successfully described by the proposed model with partially cell line specific parameters.
02 /Specification & Classification
Click any tag to browse matching papers- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Dose response relationships for gamma radiation induced chromosomal instability
Y.A. Eidelman, S.V. Slanina, … S.G. Andreev·bioRxiv·Nov 25, 2017
- DNA Damage Induced Chromosomal Instability. Computational modeling view.
Yuri A. Eidelman, Svetlana V. Slanina, … Sergey G. Andreev·bioRxiv·Nov 24, 2017
- Effects of G2 checkpoint dynamics on the low-dose hyper-radiosensitivity
O. Olobatuyi, G. de Vries, T. Hillen·bioRxiv·Sep 12, 2017
- A novel murine tail model for radiation-induced skin injury following localized irradiation at varying doses
Guojian Wang, Na Zhao, … Tao Wang·bioRxiv·Jan 10, 2025
- Chromosomal instability increases radiation sensitivity
Pippa F. Cosper, Maha Paracha, … Beth A. A. Weaver·International Journal of Radiation Oncology*Biology*PhysicsPeer-reviewed·Jan 21, 2026
- Radiation-induced cell cycle perturbations: acomputational tool validated with flow-cytometrydata
L. LONATI, S. Barbieri, … G. Baiocco·Scientific ReportsPeer-reviewed·Jan 13, 2021