bioRxivBioinformaticsPreprint
Dual-LLM Adversarial Framework for Information Extraction from Research Literature
Zhijing LiiD, Yunwen Yu, Wenhao GuiD, Tiantian ZhuiD, Haohua Song, Wenbin Guo, Yang XiaoiD, Zexuan ZhuiD
Abstract
Information Extraction (IE) is a fundamental task in Natural Language Processing (NLP) that aims to automatically identify relevant information from unstructured or semi-structured data. Information extraction from lengthy research literature, particularly in multi-omics studies, faces significant challenges due to their complex narratives and extensive context. To address this, we present a novel dual-LLM adversarial framework in which one large language model (LLM) performs the extraction and another provides iterative feedback to refine the results. This process systematically reduces errors, enhances consistency across heterogeneous data sources, and converges toward more accurate outputs. We evaluated our approach against manual and single-LLM extraction, using LLMs as evaluators. Experimental results show that our adversarial framework outperforms these baselines, highlighting its effectiveness for extracting structured information from lengthy scientific texts.
- Citations
- 0
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- OmniExtract: An automatic data extraction tool based on Large Language Model and Prompt Engineering
Yibo Wang, Bixia Tang, … Wenming Zhao·Briefings in BioinformaticsPeer-reviewed·Sep 1, 2026
- MetaBeeAI: an AI pipeline for structured evidence extraction from biological literature
Rachel H. Parkinson, Henry Cerbone, … Stephen J. Roberts·Ecological InformaticsPeer-reviewed·May 21, 2026
- Assessing the Performance of LLMs in Multimodal Information Extraction for Biological Research: A Case Study on LLPS
Ka Yin Chin, Satoru Fujii, … Kei Terayama·bioRxiv·Oct 29, 2025
- Multi-Model LLM Architectures for Personalized Summarization and Relevance Ranking in Biomedical Literature
Avinash Pandey, Alexey S. Kuznetsov, Snehasis Mukhopadhyay·bioRxiv·Jul 29, 2025
- Schema-Grounded Multitask Instruction Fine-tuning for Joint Biomedical Named Entity Recognition and Relation Extraction in Pharmacovigilance
Hasin Rehana, Junguk Hur·bioRxiv·Aug 6, 2026
- Quantifying Scientific Consensus in Biomedical Hypotheses via LLM-Assisted Literature Screening
Uiyun Kim, Ohhyeon Kwon, Doheon Lee·bioRxiv·Apr 9, 2026