Environmental MicrobiomeBioinformaticsPeer-reviewed journal article
Tax4Fun2: a R-based tool for the rapid prediction of habitat-specific functional profiles and functional redundancy based on 16S rRNA gene marker gene sequences
Franziska WemheueriD, Jessica Alison TayloriD, Rolf DanieliD, Emma L. JohnstoniD, Peter MeinickeiD, Torsten ThomasiD, Bernd WemheueriD
Abstract
Main text Main text Methods Statistical data analysis Data availability Author Contributions Competing interests References Assessing the functional capability and redundancy of a microbial community is a major challenge in environmental microbiology. To address this challenge, we developed Tax4Fun2, a R-based tool for the rapid prediction of functional profiles and functional redundancy of prokaryotic communities from 16S rRNA gene sequences. By incorporating user-defined, habitat-specific genomic information, the accuracy and robustness of predicted functional profiles can be substantially enhanced.\n\nMicroorganisms play a key role in ecosystem functioning1. High-throughput sequencing of 16S rRNA genes is a powerful and widely used approach to study the composi ...
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