Author

Ian B. Jeffery

University College CorkORCID 0000-0001-9183-7292Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Agnieszka SkowyraiD· 1 shared Amanda J. LohaniD· 1 shared Ana Ramón-Vázquez· 1 shared Andrew J. LindsayiD· 1 shared Bradford L. McRae· 1 shared Ciaran M. LeeiD· 1 shared Fergus ShanahaniD· 1 shared Janaki VelmuruganiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Agnieszka SkowyraORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 29, 2025

IL-32 drives inflammatory responses in IFN-γ primed human macrophages via a Myddosome-dependent pathway and is elevated in COVID-19

Ana Ramón-Vázquez, Agnieszka Skowyra, Tadhg Crowley…·Kenneth Nally

This study identifies IL-32β as a ligand that primes human macrophages for M1-like inflammatory responses via a Myddosome-dependent pathway and shows elevated IL-32 in severe COVID-19.

DOI 10.1101/2025.05.29.656795

humanproteomics

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BioinformaticsBMC BioinformaticsPeer-reviewedFeb 18, 2020

IPCO: Inference of Pathways from Co-variance analysis

Mrinmoy Das, Tarini Shankar Ghosh, Ian B. Jeffery

IPCO infers microbiome functionality from 16S profiles without reference genomes, outperforming existing methods and replicating biological signals from shotgun and metabolite data.

5 citations

metagenomicsstatistical model

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