Biomedical MicrodevicesBioengineeringPeer-reviewed journal article
Two-Photon Lithography-Fabricated Deterministic Lateral Displacement Microfluidic System for Efficient Minicell Purification in Cancer Therapy
Sharaj Hegde Sharavu, Sagar BhagwatiD, Sebastian KluckiD, Büsra Merve Kirpat Konak, Barbara Di VenturaiD, Pegah PezeshkpouriD, Bastian Ernst RappiD
Abstract
Chromosome-less minicells, derived from aberrant polar division events of bacterial cells, have emerged as promising nanocarriers for targeted cancer drug delivery due to their unique characteristics. A major challenge in their purification process lies in effectively isolating such spherical minicells ( View larger version (75K): org.highwire.dtl.DTLVardef@696f37org.highwire.dtl.DTLVardef@4c2aaorg.highwire.dtl.DTLVardef@883752org.highwire.dtl.DTLVardef@e7f513_HPS_FORMAT_FIGEXP M_FIG C_FIG
- Citations
- 3
- FWCI
- 0.73
- Field percentile
- top 35%
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- A cost-effective way to design a two-layered cell trapping microfluidic device
J. M. Lazaro·bioRxiv·May 29, 2021
- Printed Droplet Microfluidics for on demand dispensing of picoliter droplets and cells
R. H. Cole, S.-Y. Tang, … A. R. Abate·bioRxiv·Jul 21, 2017
- Ridge-assisted Micro Positioning of Cells and Particles in a Microchannel
Adriana Payan-Medina, Victor R. Putaturo, … Avanish Mishra·bioRxiv·Sep 26, 2025
- Modeling of Deformable Cell Separation in a Microchannel with Sequenced Pillars
S. J. Hymel, H. Fukioka, D. B. Khismatullin·bioRxiv·Mar 1, 2021
- A radial pillar device (RAPID) for continuous and high-throughput separation of multi-sized particles
N. D. Mehendale, O. Sharma, … D. Paul·bioRxiv·Oct 2, 2017
- Targeted Vibration-Induced Necrosis in Cancer Cells using Paramagnetic Microrobots
S. Mallick, M. Sokolich, … S. Das·bioRxiv·Oct 19, 2022