HPAanalyze: An R Package that Facilitates the Retrieval and Analysis of The Human Protein Atlas Data

BackgroundThe Human Protein Atlas (HPA) aims to map human proteins via multiple technologies including imaging, proteomics and transcriptomics. Access of the HPA data is mainly via web-based interface allowing views of individual proteins, which may not be optimal for data analysis of a gene set, or automatic retrieval of original images.\n\nResultsHPAanalyze is an R package for retrieving and performing exploratory analysis of data from HPA. HPAanalyze provides functionality for importing data tables and xml files from HPA, exporting and visualizing data, as well as downloading all staining images of interest. The package is free, open source, and available via Bioconductor and Github.\n\nConclusionsHPAanalyze integrates into the R workflow via the tidyverse philosophy and data structures, and it can be used in combination with Bioconductor packages for easy analysis of HPA data.