Interference with HIV infection of the first cell is essential for viral clearance in a pre-exposure prophylaxis model
Ana Moyano, Gila Lustig, Hylton E. Rodel, Tibor Antal A, Alex Sigal
The paper develops a mathematical model to predict HIV infection clearance with PrEP, showing that reducing infection frequency per cell is more effective than reducing viral burst size.
bioRxiv · Oct 5, 2018 · PreprintBioinformatics