Natural volatiles causing inhibition of mosquito biting behaviors: development of a virtual screening platform predicting antagonists of ORco function for accelerated discovery
Georgia Kythreoti, Trias N. Thireou, Christos Karoussiotis, Zafiroula Georgoussi, Panagiota G.V. Liggri, Dimitrios Papachristos, Αntonios Michaelakis, Vasileios Karras, Spyros E. Zographos, Stefan Schulz, Kostas Iatrou
The paper develops a virtual screening platform combining pharmacophore and SVM models to identify natural volatiles that inhibit mosquito ORco function, leading to the discovery of new vector control agents.
Journal of Biological Chemistry · Oct 30, 2024Peer-reviewedMolecular Biology