Αntonios Michaelakis

AgamOBP4-targeted drug repurposing identifies novel mosquito repellent scaffolds

The paper identifies novel mosquito repellents by repurposing drugs and food-derived compounds targeting AgamOBP4, with benzoyl peroxide showing strong repellency.

Natural volatiles causing inhibition of mosquito biting behaviors: development of a virtual screening platform predicting antagonists of ORco function for accelerated discovery

The paper develops a virtual screening platform combining pharmacophore and SVM models to identify natural volatiles that inhibit mosquito ORco function, leading to the discovery of new vector control agents.

Volatile allosteric antagonists of mosquito odorant receptors inhibit normal odor-dependent behaviors

The paper identifies volatile organic compounds that act as allosteric antagonists of mosquito odorant receptors, inhibiting odor-dependent behaviors and repelling multiple mosquito species.