Dog-human gene network colocalization links synaptic signalling and ubiquitination to compulsive disorders
Katarina Tengvall, Vista Sohrab, Matthew J. Christmas, Gustaf Brander, Eric Pederson, Raphaela Pensch, Brittney Kenney, 宋诚诚, Ola Wallerman, Elisabeth Sundström, Chao Wang, Asa Karlsson, Linnea L Monsen, PGC TS/OCD working group, Kathryn A. Lord, , Kerstin Lindblad‐Toh
This paper uses GWAS in dogs and humans to identify a gene network linked to compulsive disorders, revealing biological pathways not detectable in human studies alone.
bioRxiv · Oct 12, 2026 · PreprintGenetics