Chao Wang

This paper uses GWAS in dogs and humans to identify a gene network linked to compulsive disorders, revealing biological pathways not detectable in human studies alone.

The paper presents a single nuclei RNA sequencing resource of dog brain cells, identifying cell types and revealing differences in opioid receptor expression compared to humans and mice.

The paper uses evolutionary constraint scores to identify functional genomic regions and finds they are enriched for variants associated with common diseases.

The paper presents a new long-read dog genome assembly that reduces gaps and identifies thousands of previously hidden exons and functional elements.

The paper compares genomic features of canine and human angiosarcoma, finding shared genes and pathways, suggesting dogs as a valuable model for studying this cancer.