A rapid, low-cost approach to solid immersion lens fabrication for enhanced resolution in optical microscopy
Liam M. Rooney, Jay L. Christopher, Shannan Foylan, Charlie Butterworth, Laura S. Copeland, Lewis D. Walker, Katie Coubrough, Gwyn W. Gould, Margaret Cunningham, Ralf Bauer, Gail McConnell
This paper presents a low-cost, rapid method to fabricate solid immersion lenses (SILs) that enhance optical microscope resolution, achieving performance comparable to commercial glass SILs at a fraction of the cost.
bioRxiv · Feb 20, 2026 · PreprintBiophysics