Scientific Measurement and Uncertainty Evaluation

Assessing measurement uncertainty at laboratory network scale and its impact on diagnostic performance in the absence of a gold standard: application to ELISA tests for Coxiella burnetii in ruminants

The paper assesses measurement uncertainty in ELISA tests for Coxiella burnetii in ruminants without a gold standard, showing its impact on diagnostic performance and the importance of harmonizing laboratory practices.

CCQM-P199: Interlaboratory comparability study of HIV-1 RNA copy number quantification

This study evaluates interlaboratory reproducibility of HIV-1 RNA quantification methods, finding significant variation in results and highlighting the need for improved RNA material characterization.

CCQM-P199b: Interlaboratory comparability study of SARS-CoV-2 RNA copy number quantification

This study evaluates the comparability of SARS-CoV-2 RNA quantification methods across laboratories using RT-dPCR and highlights factors affecting interlaboratory variation.