Inadequate antibody validation places substantial numbers of animal and human tissue samples at risk of waste
Michael Biddle, Jemma Cooper, Katherine Blades, Dominic Ruddy, Eva Maria Krockow, Harvinder S Virk
Of 760 papers using 35 antibodies that failed knockout-controlled testing in every application, 15.8% showed validation; the other 640 used at least 8,064 animal and 4,424 human tissue samples.
PLoS Biology · Oct 6, 2026Peer-reviewedCell Biology✦ In-depth digest