Enzyme-responsive Hemostatic Elastin-like Polypeptides for Fibrin Stabilization and Coagulation Restoration in Thrombocytopenia
Yang Sun, Shin-Hae Kang, Malvina Heiniger, Ivan Urosev, Rosario Vanella, Adrian Bertschi, Michael A. Nash
This paper develops enzyme-responsive elastin-like polypeptides to stabilize fibrin clots and restore coagulation in thrombocytopenia by enhancing clot mechanics and reducing blood loss.
Journal of the American Chemical Society · Jan 28, 2026Peer-reviewedBioengineering