Rosario Vanella

This study identifies Scf1 as a C. auris adhesin that binds multiple human proteins and shows that shear stress influences its ligand preference.

This paper develops enzyme-responsive elastin-like polypeptides to stabilize fibrin clots and restore coagulation in thrombocytopenia by enhancing clot mechanics and reducing blood loss.

This study investigates how environmental factors and mutations affect the stability and scalability of catch bond complexes between SdrG and fibrinogen beta chain using single-molecule and multi-valent adhesion assays.

This study uses deep mutational learning to identify myoglobin variants with enhanced peroxidase activity, showing the role of electron-hole hopping in catalytic efficiency.

The paper uses enzyme proximity sequencing to map how mutations affect substrate specificity of DAOx, identifying key positions and combinations that enhance selectivity.

This study shows how modifying anchor points on Anticalin scaffolds improves binding strength and adhesion to CTLA-4 under shear stress, enhancing targeted drug delivery.

This study uses deep mutational scanning to identify mutations that enhance thermostability in human myoglobin, discovering a de novo disulfide bond and combinatorial mutations that significantly increase stability.

The paper develops an integrated method combining dynamic network analysis with AI to predict epitopes in PD-L1:Affibody interactions, showing the perpendicular binding mode is more stable.