Early and current environments exert distinct effects on immune function in the Orang Asli
Layla Brassington, Audrey M. Arner, Grace Rodenberg, Nicholas Ryan, Diane Song, Tan Bee Ting A P Tan Boon Huat, Virginia B. Kraus, Janet L. Huebner, Izandis bin Mohd Sayed, Yvonne AL Lim, Vivek V. Venkataraman, Ian J. Wallace, Thomas S. Kraft, Amanda J. Lea
The paper examines how early-life and current environments affect immune function in the Orang Asli, finding current lifestyle has stronger effects on immune gene expression than early-life conditions.
bioRxiv · Jul 30, 2026 · PreprintGenetics