Discover, rate, and discuss biology preprints.

The paper estimates malaria transmission risk in sub-Saharan Africa over 74 kya and shows humans avoided malaria hotspots, shaping demography and population structure.

The paper uses whole chloroplast genomes to trace the genetic history of Fagus, revealing ancient lineages, past radiations, and genetic admixture events.

This paper introduces and validates population sequencing methods to analyze phylogenetic diversity in bacterial populations without haplotype reconstruction, demonstrating applications in tracking transmission and understanding pathogen dynamics.

The paper investigates the relationship between gene family expansions and metabolic traits in yeasts, finding that keystone gene families drive multiple metabolic innovations.

This study uses deep learning to analyze pollen morphology and links it to environmental factors and phylogenetic history in Podocarpus species.

CladeOScope-GSA predicts functional gene interactions using phylogenetic profiling across 1905 species, offering enhanced analysis and visualization tools for comparative genomics.

This paper introduces a scalable framework to quantify and map genetic diversity across multiple species, identifying hotspots of diversity linked to evolutionary history and climate stability.

The paper compares the genetic impacts of natural dispersal and translocation in eastern black rhinoceros, finding lower inbreeding in dispersers but higher deleterious mutation load in translocated offspring.

The paper quantifies genetic diversity across 93 marine species and finds that range size and planktonic dispersal correlate with higher genetic diversity.

This study examines sensory system tradeoffs in subterranean salamanders, finding degeneration of eyes and expansion of lateral line systems across multiple lineages.

This paper develops a framework to detect and quantify sexual reproduction in populations by addressing biases in genomic data analysis, using ancestral recombination graphs and simulation models.

The paper analyzes the phylogenetic position of extinct Hawaiian honeyeaters using ultraconserved elements, overcoming issues with degraded DNA by re-aligning and re-assembling data.

The paper shows that optimal antimicrobial dosing combinations depend on the relative mutation rates of drugs, with a linear relationship in log-log space between dose ratios and mutation rate ratios.

This study identifies carotenoid-rich coelomocytes in sea cucumbers, challenging the assumption that hemocytes contain haemoglobin and proposing a new classification as carotenocytes.

The paper measures nuclear genome size variation in Potamopyrgus antipodarum, finding higher genome content in sexual individuals and evidence for a recent whole-genome duplication.

The paper uses spatial simulations to detect selective sweeps in Anopheles gambiae and identifies new variants under selection.

The paper examines how host competitive asymmetries affect viral evolution in a co-evolutionary system, finding that they extend viral extinction times and accelerate adaptation.

This study finds that two matings in female Drosophila melanogaster cause more genital and abdominal wounds than a single mating.

This study describes a new predatory flagellate species, Glissandra oviformis, and uses phylogenomic analysis to place it within the CRuMs clade, contributing to understanding character evolution in this group.

This study uses population genomics to guide coral reef restoration by analyzing genetic diversity and connectivity in staghorn corals in Micronesia, identifying key populations for conservation and restoration strategies.