BiochemistryNaturePeer-reviewed
✦ In-depth digest
Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models
Joseph L. Watson, David Juergens, Nathaniel R. Bennett…·David A. Baker
Fine-tuning RoseTTAFold as a diffusion denoiser gives RFdiffusion, a general protein backbone generator; a designed influenza haemagglutinin binder matched its model by cryo-EM.
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