Author

Łukasz Paszkowski

Simula Research Laboratory

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Systems Biology· 1

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Approach:statistical model· 1

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Daniel WeindliD· 1 shared Dilan PathiranaiD· 1 shared Fabian FröhlichiD· 1 shared Glenn Terje LinesiD· 1 shared Jan HasenaueriD· 1 shared Paul L. StaporiD· 1 shared Polina LakrisenkoiD· 1 shared Stephan GreiniD· 1 shared

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2023-2023 · peak 1/yr

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Daniel WeindlORCID

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1 paper

Recent·Most cited

Efficient computation of adjoint sensitivities at steady-state in ODE models of biochemical reaction networks

Polina Lakrisenko, Paul L. Stapor, Stephan Grein, Łukasz Paszkowski, Dilan Pathirana, Fabian Fröhlich, Glenn Terje Lines, Daniel Weindl, Jan Hasenauer

The paper introduces a new adjoint method for computing gradients in ODE models of biochemical reaction networks using steady-state data, achieving up to 4.4x speedup in simulation time for large-scale models.

PLoS Computational Biology · Jan 3, 2023Peer-reviewedSystems Biology