Actively Protective Combinatorial Analysis: a Scalable Novel Method for Detecting Variants that Contribute to Reduced Disease Prevalence in High-Risk Individuals
Jason M. Sardell, Sayoni Das, K Taylor, Colin R. Stubberfield, A Malinowski, Mark A. Strivens, Steve Gardner
This paper introduces a method to detect genetic variants that reduce disease risk in high-risk individuals, identifying protective signatures that could inform drug targets and precision medicine.
Artificial Intelligence in the Life Sciences · Jan 31, 2025Peer-reviewedGenetic & Genomic Medicine