Author

Mark A. Strivens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:GWAS summary statistics· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Sayoni DasiD· 3 shared Steve GardneriD· 2 shared A Malinowski· 1 shared Alpha Tom KodamulliliD· 1 shared Andrea ZalianiiD· 1 shared Bruce T. SchultziD· 1 shared Carsten ClausseniD· 1 shared Christian EbelingiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetic & Genomic Medicine

Sayoni DasORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Actively Protective Combinatorial Analysis: a Scalable Novel Method for Detecting Variants that Contribute to Reduced Disease Prevalence in High-Risk Individuals

Jason M. Sardell, Sayoni Das, K Taylor, Colin R. Stubberfield, A Malinowski, Mark A. Strivens, Steve Gardner

This paper introduces a method to detect genetic variants that reduce disease risk in high-risk individuals, identifying protective signatures that could inform drug targets and precision medicine.

Artificial Intelligence in the Life Sciences · Jan 31, 2025Peer-reviewedGenetic & Genomic Medicine

The COVID-19 PHARMACOME: A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization

Bruce T. Schultz, Andrea Zaliani, Christian Ebeling, Jeanette Reinshagen, Denisa Bojková, Vanessa Lage‐Rupprecht, Reagon Karki, Soeren Lukassen, Yojana Gadiya, Neal G. Ravindra, Sayoni Das, Shounak Baksi, Daniel Domingo‐Fernándéz, Manuel Lentzen, Mark A. Strivens, , Martin Hofmann‐Apitius

The paper presents a drug-target-mechanism graph to identify synergistic drug combinations for SARS-CoV-2 treatment, validated through experimental testing.

bioRxiv · Sep 23, 2020 · PreprintBioinformatics

Analysis of Genetic Host Response Risk Factors in Severe COVID-19 Patients

Krystyna Taylor, Sayoni Das, Matthew W Pearson, James A. Kozubek, Marcin Pawłowski, Claus Erik Jensen, Zbigniew Skowron, Gert Lykke Møller, Mark A. Strivens, Steve Gardner

This study identifies 68 genetic risk factors associated with severe COVID-19 using combinatorial analysis, highlighting pathways like calcium signaling and potential drug targets.

medRxiv · Jun 17, 2020 · PreprintGenetic & Genomic Medicine