Defining dysfunction due to loss of MECP2 in Rett Patient Brain
Elena Korsakova, A Morales, T McDaniel, A Lund, B Cooper, F Ma, TF Allison, Kathrin Plath, NA Graham, Aparna Bhaduri, William E. Lowry
The paper develops a single-nuclei RNA sequencing approach to study MECP2 dysfunction in Rett Syndrome, identifying aberrant gene expression and a role for POU2F1/OCT1 in stress response.
bioRxiv · Aug 24, 2021 · PreprintMolecular Biology