IPF distal lung epithelial cells acquire a DNA methylation signature consistent with activation of basal cell transcriptional programs
Arlo C. Colvard, Stefano A. Iantorno, Isabella P. Gaona, M. Merced Malabanan, Taylor S Sherrill, Rafael Jesus Fernandez, Ciara M. Shaver, Lorraine B. Ware, Bradley W. Richmond, Jennifer M. S. Sucre, Nicholas E. Banovich, A Scott McCall, Jonathan A. Kropski, Jason J. Gokey
The paper identifies DNA methylation changes in IPF lung epithelial cells linked to dysregulated transcriptional programs and impaired repair.
bioRxiv · Sep 22, 2026 · PreprintMolecular Biology