Bradley W. Richmond

The paper identifies clade B serpins as drivers of basal-to-goblet cell differentiation in COPD, linking them to goblet cell hyperplasia and inflammatory signaling.

The paper identifies DNA methylation changes in IPF lung epithelial cells linked to dysregulated transcriptional programs and impaired repair.

Single-cell RNA-sequencing identifies distinct epithelial and mesenchymal cell types and their roles in pulmonary fibrosis.

This paper develops a clinical phenotyping algorithm to identify COPD cases in EHRs using ICD codes, achieving high sensitivity and negative predictive value.