Author

A Sigen

Anhui University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Ana B. Enguita· 1 shared Ángeles MencíaiD· 1 shared Diana de Prado-VerdúniD· 1 shared Enrique RecueroiD· 1 shared Irene Lara‐SáeziD· 1 shared Marta GarcíaiD· 1 shared Marta Ines GallegoiD· 1 shared Marta OteoiD· 1 shared

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1 shared paperCancer Biology

Ana B. Enguita

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 3, 2024

Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models

Irene Lara‐Sáez, Ángeles Mencía, Enrique Recuero…·Mirentxu Santos

This paper introduces a non-viral CRISPR/Cas9 method using cationic polymers to generate mouse lung cancer models by inactivating tumor suppressor genes, enabling rapid and flexible hypothesis testing.

6 citations

mouseCRISPR screen

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