Prevention of mRNA vaccine-induced anaphylaxis by peripheral cyclooxygenase inhibitors in an anti-PEG hyperimmune pig model: clinical relevance for nanomedicine-induced infusion reactions
Bálint András Barta, Tamás Radovits, Attila Balázs Dobos, Sylvia Spiesshofer, A Toth, Gleb Kornev, Alberto Gabizon, Bela Merkely, János Szebeni
This study identifies cyclooxygenase inhibitors as effective in preventing mRNA vaccine-induced anaphylaxis in a hyperimmune pig model, suggesting potential clinical applications for nanomedicine infusion reactions.
bioRxiv · May 29, 2026 · PreprintImmunology