Neuronal activation affects the organization and protein composition of the nuclear speckles
A. A. Szczepankiewicz, K. Parobczak, M. Zareba-Koziol, B. Ruszczycki, M. Bijata, P. Trzaskoma, G. Hajnowski, D. Holm-Kaczmarek, J. Wlodarczyk, G. M. Wilczynski, M. J. Redowicz, A. Magalska
This study shows neuronal activation remodels nuclear speckles' organization and protein composition in rat hippocampal neurons without causing stress or cell death, and these changes depend on transcription and splicing.
bioRxiv · Mar 25, 2024Cell Biology