Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection
J. B. Kadji Fassi, H. Boukeng Jatsa, U. Membe Femoe, V. Greigert, J. Brunet, C. Cannet, C. M. Kenfack, N. Gipwe Feussom, E. Tienga Nkondo, A. Abou-Bacar, A. W. Pfaff, R. Kamgang, P. Kamtchouing, L.-A. Tchuem Tchuente
This study shows that protein undernutrition in mice reduces praziquantel's effectiveness against Schistosoma mansoni infection by worsening liver damage, oxidative stress, and immune responses.
bioRxiv · Feb 14, 2022Pathology