Author

A. Altendorf-Hofmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. F. Orth· 2 shared T. G. P. Grunewald· 2 shared T. Kirchner· 2 shared A. Marchetto· 1 shared E. Butt· 1 shared E. Kampmann· 1 shared E. Noessner· 1 shared F. Cidre-Aranaz· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

M. F. Orth

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2 papers

Recent·Most cited

Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas

M. F. Orth, V. L. Buecklein, E. Kampmann, M. Subklewe, E. Noessner, F. Cidre-Aranaz, L. Romero-Perez, F. S. Wehweck, L. Lindner, R. Issels, T. Kirchner, A. Altendorf-Hofmann, T. G. P. Grunewald, T. Knoesel

This study examines PD-L1 and PD-1 expression in soft tissue sarcomas and finds associations with TILs and poor clinical outcomes, supporting immune checkpoint inhibition in PD-L1-positive cases.

bioRxiv · Mar 8, 2019 · PreprintCancer Biology

Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma

M. F. Orth, J. S. Gerke, T. Knosel, A. Altendorf-Hofmann, J. Musa, R. Alba Rubio, S. Stein, M. Dallmayer, M. C. Baldauf, A. Marchetto, G. Sannino, S. Ohmura, J. Li, M. Hakozaki, T. Kirchner, , T. G. P. Grunewald

This study identifies AMPD2 as a prognostic biomarker for undifferentiated pleomorphic sarcoma using transcriptome analysis, immunohistochemistry, and functional assays.

bioRxiv · Mar 31, 2018Pathology