Author

E. Noessner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Altendorf-Hofmann· 1 shared D. Brech· 1 shared E. Kampmann· 1 shared E. Kokolakis· 1 shared E. Schaeffeler· 1 shared F. Buettner· 1 shared F. Cidre-Aranaz· 1 shared F. S. Wehweck· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Altendorf-Hofmann

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2 papers

Recent·Most cited

A mosaic renal myeloid subtype with T-cell inhibitory and protumoral features is linked to immune escape and survival in clear cell renal cell cancer

D. Brech, T. Straub, E. Kokolakis, M. Irmler, J. Beckers, F. Buettner, E. Schaeffeler, S. Winter, M. Schwab, P. J. Nelson, E. Noessner

The paper identifies a renal myeloid subtype in clear cell renal cell cancer that exhibits immunoinhibitory and tumor-promoting features, correlates with poor patient survival, and suggests therapeutic targets.

bioRxiv · Jan 20, 2020 · PreprintImmunology

Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas

M. F. Orth, V. L. Buecklein, E. Kampmann, M. Subklewe, E. Noessner, F. Cidre-Aranaz, L. Romero-Perez, F. S. Wehweck, L. Lindner, R. Issels, T. Kirchner, A. Altendorf-Hofmann, T. G. P. Grunewald, T. Knoesel

This study examines PD-L1 and PD-1 expression in soft tissue sarcomas and finds associations with TILs and poor clinical outcomes, supporting immune checkpoint inhibition in PD-L1-positive cases.

bioRxiv · Mar 8, 2019 · PreprintCancer Biology