EZH2 inhibition enhances TRAIL responses in multiple myeloma but not in quiescent cells
A. Arhoma, J. Southan, A. D. Chantry, S. L. Haywood-Small, N. A. Cross
This study shows that EZH2 inhibition with GSK343 enhances TRAIL-induced apoptosis in multiple myeloma cell lines and 3D cultures, but not in TRAIL-resistant or quiescent cells.
bioRxiv · Jul 23, 2021 · PreprintCancer Biology