Single-cell RNA-sequencing of peripheral neuroblastic tumors reveals an aggressive transitional cell state at the junction of an adrenergic-mesenchymal transdifferentiation trajectory
X. Yuan, J. A. Seneviratne, S. Du, Y. Xu, Y. Chen, Q. Jin, X. Jin, A. Balachandran, S. Huang, Y. Xu, Y. Zhai, L. Lu, M. Tang, Y. Dong, B. B. Cheung, , D. R. Carter
This study uses single-cell RNA-sequencing to identify a transitional cell state in peripheral neuroblastic tumors associated with poor prognosis and therapeutic targets.
bioRxiv · May 15, 2020 · PreprintCancer Biology