Human primosome requires replication protein A when copying DNA with inverted repeats
A. Baranovskiy, L. Morstadt, E. E. Romero, N. Babayeva, T. H. Tahirov
This study shows RPA is critical for human primosome DNA synthesis across inverted repeats, with a specific winged helix-turn-helix domain enhancing RPA-Pol cooperation and structural integration.
bioRxiv · Mar 11, 2024 · PreprintBiochemistry