MiR-16-1* and miR-16-2* possess strong tumor suppressive and anti-metastatic properties in osteosarcoma.
V. V. Maximov, S. Khawaled, Z. Salah, L. Jaber, N. Bengaiev, A. Barhoum, M. Galasso, E. Yavin, R. I. Aqeilan
This study identifies miR-16-1* and miR-16-2* as tumor suppressors in osteosarcoma, showing they inhibit tumor growth, metastasis, and chemoresistance.
bioRxiv · Sep 9, 2018Cancer Biology