Development and Characterization of a Weaned Pig Model of Shiga Toxin-Producing E. coli-Induced Gastrointestinal Disease
J. X. Boeckman, S. Sprayberry, A. M. Korn, J. S. Suchodolski, C. Paulk, K. J. Genovese, R. R. Rech, P. R. Giarettta, A. Blick, T. Callaway, J. J. Gill
This study develops a pig model of E. coli-induced post-weaning diarrhea and evaluates chronic vs acute dosing regimens, finding chronic dosing produces similar disease outcomes with lower pathogen doses.
bioRxiv · Aug 26, 2021 · PreprintPathology