Novel roles for pirin proteins and a 2-ketoglutarate:ferredoxin oxidoreductase ortholog in Bacteroides fragilis central metabolism and comparison of metabolic mutants susceptibility to antimicrobials metronidazole and amixicile.
A. M. Gough, A. C. Parker, P. J. O'Bryan, T. R. Whitehead, S. Roy, B. L. Garcia, P. S. Hoffman, C. J. Smith, E. R. Rocha
This study identifies pirin proteins and their interaction with metabolic enzymes in B. fragilis, showing their role in antimicrobial susceptibility to metronidazole and amixicile.
bioRxiv · Apr 11, 2024Microbiology