Author

A. C. Purcell

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Fawkes· 1 shared B. J. Livesey· 1 shared E. Latorre-Crespo· 1 shared I. J. Deary· 1 shared J. A. Marsh· 1 shared K. Kirschner· 1 shared L. J. Schumacher· 1 shared L. MacGillvray· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Fawkes

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1 paper

Recent·Most cited

Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects

N. A. Robertson, E. Latorre-Crespo, M. Terrada-Terradas, A. C. Purcell, B. J. Livesey, J. A. Marsh, L. Murphy, A. Fawkes, L. MacGillvray, M. Copland, R. E. Marioni, S. E. Harris, S. R. Cox, I. J. Deary, L. J. Schumacher, , T. Chandra

This study quantifies gene-specific fitness effects of CHIP drivers over 12 years using longitudinal sequencing data and a new DIF filtering method, showing gene-specific differences can inform personalized clinical management.

bioRxiv · May 27, 2021Cell Biology