S. E. Harris

Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro

The paper examines interspecies differences in RNA-protein interactions using the neuronal RNA binding protein UNK, finding conserved binding patterns and species-specific sequence determinants.

Visualization of liquid-liquid phase transitions using a tiny G-quadruplex binding protein

The paper identifies SERF2 as a protein involved in stress granule formation and characterizes its interactions with G-quadruplex RNA structures to study liquid-liquid phase transitions.

Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects

This study quantifies gene-specific fitness effects of CHIP drivers over 12 years using longitudinal sequencing data and a new DIF filtering method, showing gene-specific differences can inform personalized clinical management.

Akr1d1-/- mice have a sexually dimorphic metabolic phenotype with reduced fat mass, increased insulin sensitivity and hypertriglyceridemia in males

This study shows that AKR1D1 controls bile acid homeostasis and affects insulin sensitivity and lipid homeostasis in a sex-dependent manner in mice.

Demographic inference provides insights into the extirpation and ecological dominance of eusocial snapping shrimps

This study uses demographic inference to show that eusocial snapping shrimps have lower but more stable population sizes, which may explain their ecological dominance but also their vulnerability to environmental changes.

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

The paper generates 24 induced pluripotent stem cell lines from members of the Lothian Birth Cohort 1936 to study cognitive ageing and neurodegenerative disease resilience.

Signatures of positive selection and local adaptation to urbanization in white-footed mice (Peromyscus leucopus)

This study identifies genetic signatures of local adaptation to urbanization in white-footed mice by analyzing transcriptomes and SNP data from urban and rural populations.