Author

A. C. von Huelsen Rocha

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. M. Warboys· 1 shared E. M. Drudi· 1 shared K. Tian Pang· 1 shared M. Ghim· 1 shared M. Rickman· 1 shared M. Sureda-Vives· 1 shared N. Ayoub· 1 shared P. D. Weinberg· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperCell Biology

C. M. Warboys

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1 paper

Recent·Most cited

Cell BiologybioRxivNov 12, 2021

Frizzled-4 regulates β-catenin in endothelial cells exposed to disturbed flow via an atypical Wnt pathway leading to proinflammatory activation and increased permeability

M. Rickman, M. Ghim, K. Tian Pang…·C. M. Warboys

This study shows that Frizzled-4 and RSPO-3 mediate an atypical Wnt pathway in endothelial cells under multidirectional flow, leading to β-catenin stabilization, inflammation, and increased permeability.

DOI 10.1242/jcs.260449

humanmouse

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